Research: Postmortem Distribution of Zolpidem in Aviation Accident Victims

Toxicological analysis performed by UPLC/MS provided accurate, precise, and rapid results that indicated the spleen, kidney, and lung all had a consistent postmortem distribution of zolpidem to that of blood.  The results of this study confirmed there is a consistent postmortem distribution of zolpidem found in the spleen, kidney, and lung.  The study also confirmed it would be possible to roughly estimate, with caution, zolpidem blood concentrations from the spleen, kidney and/or lung.  This may help determine if zolpidem was in the therapeutic, toxic, or lethal range when no blood is available.