Month: December 2020

Dr. Gang Xu’s Research Continues after U.S. Dept. of Energy Grant

In summer 2019, Dr. Gang Xu received funding from the U.S. Department of Energy for his proposal, “Flagella-Driven Cellular Motility, Transport, & Biomixing: Computational Studies.”  The funding provided Dr. Xu and two of his former research assistants, Erin Drewke and Joseph Wagner, with full support to spend 10 weeks working at the Lawrence Berkeley National Lab in Berkeley, California.  There they worked with Drs. Ann Almgren and Johannes Blaschke in its Center for Computational Sciences and Engineering to develop a novel simulation capability based on combining state-of-the-art algorithms with empirical models for beating flagella and swimming cells. The new codes are ideally suitable for high-performance computing resources such as those at the Berkeley Lab and also UCO. The results will improve the understanding on the hydrodynamic impacts of flagellar beating and flagella-actuated cell swimming, and provide biophysical and mechanistic basis for development of novel microfluidic and biofuel devices. This experience paved the way for continued collaboration and expanded Dr. Xu’s research capacity.  Erin, a 2020 UCO biomedical engineering graduate, is pursuing her Ph.D. in biomedical engineering at the University of Arkansas. Joseph, a prospective 2021 mechanical engineering graduate, is planning to pursue a Ph.D.

Research Group Investigates Gene Transfer in Bacteria

Biology professor Dr. Jim Bidlack and his research group are investigating gene transfer in bacteria. Better understanding of how bacteria become multidrug resistant can help researchers develop new techniques that can control bacterial infections and save human lives. Coincidently, a new gene locus encoding for bile salt sensitivity in bacteria appears to be the same gene locus responsible for antibiotic resistance. Dr. Bidlack’s students are currently isolating that gene locus so that it can be sequenced and determine what part of the DNA encodes for antibiotic resistance. If successful, it may be possible to use that information to develop new drugs that will be more effective in fighting bacterial infections.